TYPE II COLLAGEN-POSITIVE PROGENITORS ARE IMPORTANT STEM CELLS IN CONTROLLING SKELETAL DEVELOPMENT AND VASCULAR FORMATION

Type II collagen-positive progenitors are important stem cells in controlling skeletal development and vascular formation

Abstract Type II collagen-positive (Col2+) cells have been reported as skeletal stem cells (SSCs), but the contribution of Col2+ progenitors to skeletal development both prenatally and postnatally during aging remains unclear.To address this question, we generated new mouse models with ablation of Col2+ cells at either the embryonic or postnatal st

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ASPIRE-to-Excellence Academy

The ASPIRE-to-Excellence Academy was recently founded at the 2015 Association for Medical Education in Europe (AMEE) conference in Glasgow.The academy is new pillar of the ASPIRE-to-Excellence initiative by AMEE, which aims at promoting and encouraging medical schools in achieving excellence in the categories of assessment, student engagement, soci

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Stochastic Risk Assessment with a Lagrangian Solution for the Optimal Cost Allocation in High-Speed Rail Networks

In large-scale high-speed rail networks (HSRNs), the occurrence of occasional malfunctions or accidents is unavoidable.The key issue considered in this study is the optimal allocation of the maintenance costs, based on the stochastic risk assessment for HSRNs.Inspired by the theoretical risk evaluation methods in the complex network, three major fa

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